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Francis Lévi, Warwick Medical School, University of Warwick, July 21, 2014:

- Circadian control of xenobiotic carcinogenesis and cancer pharmacology

- Toward Systems Cancer Chronotherapeutics and its integration into home care 

La Société Francophone de Chronobiologie (SFC) organise son 44ème congrès qui se déroulera du 29-31 octobre 2014

Séance de la Société de Biologie " La chronobiologie " aura lieu le 15 octobre 2014 de 15h00 à 18h00 Institut Curie-Pavillon Curie Amphithéâtre Marie Curie 11, rue Pierre et Marie Curie – Paris 5ème

La soutenance de thèse de Melle Véronique ROCHE sera présentée le 21 mai 2014

Reportage BBC, 13 mai 2014  Chronotherapy: The science of timing drugs to our Body

Journal "Le monde" le 30 avril 2014, "Quand l'horloge biologique se détraque"

 

Voir la suite

Contact

UMRS 935

Equipe3 : Chronothérapie des cancers

et optimisation de la fonction hépatique

INSERM et Université Paris Sud

Bât A 3ème étage Campus CNRS
7 rue Guy Môquet
94801 Villejuif Cedex (France)
Tel :  +33 (0) 1 49 58 34 83
Fax : +33 (0) 1 49 58 34 59
Email:gladys.germe@inserm.fr

Home Production scientifique Publication

2013

 

Allard M.A., Adam R., Ruiz A ,Vibert E., Paule B., Levi F., Sebagh M., Guettier C., Azoulay D., Castaing D. : Is still unexpected Peritoneal Carcinomatosis a contraindication to resection of colorectal liver metastases? Combined resection of colorectal liver metastases with peritoneal deposits discovered intra-operatively.Eur. J. Surg. Oncol., 2013, 39 (9) : 981-987 ; Jul 8. [Epub ahead of print].

A. Ballesta, M. Doumic-Jauffret, J. Lopez, P. Gonzalo, G. Gillet: Data-driven modeling of SRC control on the mitochondrial pathway of apoptosis: implication for anticancer therapy optimization, PLoS Computational Biology,  2013 Apr;9(4):e1003011. doi: 10.1371/journal.pcbi.1003011. Epub 2013 Apr 4.

A. Ballesta, J. Clairambault, S. Dulong, F. Levi: A systems biomedicine approach for chronotherapeutics optimization: focus on the anticancer drug irinotecan. In: New Challenges for Cancer Systems Biomedicine, SIMAI Lecture Notes, Springer, New York, in press, 2013.

Billy, F., Clairambault, J., Delaunay, F., Feillet, C., Robert, N. Age-structured cell population model to study the influence of growth factors on cell cycle dynamics. Mathematical Biosciences and Engineering, 10(1):1-17, 2013

Billy, F., Clairambault, J., Fercoq, O. Optimisation of cancer drug treatments using cell population dynamics. pp. 257-299 in "Mathematical Models and Methods in Biomedicine'', A. Friedman, E. Kashdan, U. Ledzewicz and H. Schättler eds., Part 4, pp. 265-309, Springer, New-York, 2013.

Billy, F., Clairambault, J. Designing proliferating cell population models with functional targets for control by anti-cancer drugs. DCDS-B, 18(4):865-889, 2013. In Special issue on cancer modelling

Billy, F., Clairambault, J., Fercoq, O., Gaubert, S., Lepoutre, T., Ouillon, T., Saito, S. Synchronisation and control of proliferation in cycling cell population models with age structure. Mathematics and Computers in Simulation, in press, 2013, http://dx.doi.org/10.1016/j.matcom.2012.03.005.

Costa MJ, Finkenstädt BF, Gould PD, Foreman J, Halliday K, Hall A, Roche V, Lévi F, Rand DA; Inference on periodicity of circadian time series. Biostatistics 2013, 2013 Sep;14(4):792-806. doi: 10.1093/biostatistics/kxt020. Epub 2013 Jun 6.

Dimitrio, L., Clairambault, J., Natalini, R. A spatial physiological model for p53 intracellular dynamics. Journal of Theoretical Biology, 316:9-24, 2013

Innominato PF, Giacchetti S, Moreau T, Bjarnason GA, Smaaland R, Focan C, Garufi C, Iacobelli S, Tampellini M, Tumolo S, Carvalho C, Karaboué A, Poncet A, Spiegel D, Lévi F; for the International Association for Research on Time in Biology and Chronotherapy (ARTBC) Chronotherapy Group. Fatigue and weight loss predict survival on circadian chemotherapy for metastatic colorectal cancer. Cancer. 2013 Apr 30. doi: 10.1002/cncr.28072.

Li XM, Mohammad-Djafari A, Dumitru M, Dulong S, Filipski E, Siffroi-Fernandez S, Mteyrek A, Scaglione F, Guettier C, Delaunay F, Lévi F: A circadian clock transcription model for the personalization of cancer chronotherapy. Cancer Res December 15, 2013 73:7176-7188

Lorz, A., Lorenzi, T., Hochberg, M.E., Clairambault, J., Perthame, B. Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies. Mathematical Modelling and Numerical Analysis, 47:377-399, 2013. DOI: http://dx.doi.org/10.1051/m2an/2012031

Ortiz-Tudela E, Mteyrek A, Ballesta A, Innominato PF, Lévi F. : Cancer chronotherapeutics. Experimental, theoretical and clinical aspects. In "Circadian clocks. Handbook of Experimental Pharmacological Series". A. Kramer and M. Merrow (eds.), Handbook of Experimental Pharmacology, Springer-Verlag Berlin Heidelberg; 2013, 217, DOI 10.1007/978-3-642-25950-0_12.

Palesh O, Aldridge-Gerry A, Ulusakarya A, Ortiz-Tudela E, Capuron L, Innominato PF. Sleep disruption in breast cancer patients and survivors. J Natl Compr Canc Netw. 2013 Dec 1;11(12):1523-30. Review. PubMed PMID: 24335687.

 


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