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Francis Lévi, Warwick Medical School, University of Warwick, July 21, 2014:

- Circadian control of xenobiotic carcinogenesis and cancer pharmacology

- Toward Systems Cancer Chronotherapeutics and its integration into home care 

La Société Francophone de Chronobiologie (SFC) organise son 44ème congrès qui se déroulera du 29-31 octobre 2014

Séance de la Société de Biologie " La chronobiologie " aura lieu le 15 octobre 2014 de 15h00 à 18h00 Institut Curie-Pavillon Curie Amphithéâtre Marie Curie 11, rue Pierre et Marie Curie – Paris 5ème

La soutenance de thèse de Melle Véronique ROCHE sera présentée le 21 mai 2014

Reportage BBC, 13 mai 2014  Chronotherapy: The science of timing drugs to our Body

Journal "Le monde" le 30 avril 2014, "Quand l'horloge biologique se détraque"

 

Voir la suite

Contact

UMRS 935

Equipe3 : Chronothérapie des cancers

et optimisation de la fonction hépatique

INSERM et Université Paris Sud

Bât A 3ème étage Campus CNRS
7 rue Guy Môquet
94801 Villejuif Cedex (France)
Tel :  +33 (0) 1 49 58 34 83
Fax : +33 (0) 1 49 58 34 59
Email:gladys.germe@inserm.fr

Home Production scientifique Publication

2014

 

A. Ballesta, J. Clairambault, Physiologically based mathematical models to optimize therapies against metastatic colorectal cancer: a mini-review, Current Pharmaceutical Design, 2014;20(1):37-48.

Feillet C., Krusche P., Tamanini F., Janssens R., Downey M, Martin P., Teboul M., Saito S., Lévi F., Bretschneider T., van der Horst G.T.J., Delaunay F.,. Rand D. A. Phase-locking and multiple attractors for the coupled mammalian clock and cell cycle. Proc Natl Acad Sci USA 2014 Jul 8;111(27):9828-33. doi: 10.1073/pnas.1320474111. Epub 2014 Jun 23.

Filipski E., Berland E., Ozturk N., van der Horst G.T., Guettier C., Lévi F., Okyar A.:  Optimization of irinotecan chronotherapy with P-glycoprotein inhibition. Toxicol Appl Pharmacol. 2014 Feb 1;274(3):471-9. doi: 10.1016/j.taap.2013.12.018. Epub 2013 Dec 29.

Innominato PF, Roche VP, Palesh OG, Ulusakarya A, Spiegel D, Lévi FA. The circadian timing system in clinical oncology. Ann Med. 2014 Jun;46(4):191-207.doi: 0.3109/07853890.2014.916990. PubMed PMID: 24915535.

Lévi F, Dugué PA, Innominato P, Karaboué A, Dispersyn G, Parganiha A, Giacchetti S, Moreau T, Focan C, Waterhouse J, Spiegel D, on behalf of the ARTBC Chronotherapy Group: Wrist actimetry circadian rhythm as a robust predictor of colorectal cancer patients survival. Chronobiol Int. 2014 Oct;31(8):891-900. doi: 10.3109/07420528.2014.924523. Epub 2014 Jun 13

Mteyrek A., Filipski E., Guettier C., Lévi F.: Clock gene Per2 as a controller of liver carcinogenesis hallmarks. Soumis pour publication

Elisabet Ortiz-Tudela, Ida Iurisci, Jacques Beau, Abdoulaye Karaboue, Thierry Moreau, Maria Angeles Rol, Juan Antonio Madrid, Francis Lévi and Pasquale F. Innominato. The circadian rest-activity rhythm, a potential safety pharmacology endpoint of cancer chemotherapy. International Journal of Cancer. 2014 Jun 1;134(11):2717-25. doi: 10.1002/ijc.28587. Epub 2013 Nov 25.

Roche V., Mohamad-Djafari A., Innominato P., Karaboué A., Gorbach A., Lévi F. : Thoracic surface temperature rhythm as a circadian biomarker for cancer chronotherapy. Chronobiol Int. 2014 Apr;31(3):409-20. doi: 10.3109/07420528.2013.864301. Epub 2014 Jan.

Siffroi-Fernandez, S., Dulong S., Li X.M., Filipski E., Gréchez-Cassiau A., Peteri-Brünback B., Meijer L., Lévi F., Teboul M., Delaunay F. Functional genomics identify Birc5/survivin as a candidate gene involved in the chronotoxicity of cyclin-dependent kinase inhibitors. Cell Cycle. 2014 Mar 15;13(6):984-91. doi: 10.4161/cc.27868. Epub 2014 Jan 21.

Jegatheeswaran S, Jamdar S, Satyadas T, Sheen AJ, Adam R, Siriwardena AK. Use  of Pharmacologic Agents for Modulation of Ischaemia-Reperfusion Injury after Hepatectomy: A Questionnaire Study of the LiverMetSurvey International Registry of Hepatic Surgery Units. HPB Surg. 2014;2014:437159. Epub 2014 Nov 12.  PubMed PMID: 25477707.

Zaouali MA, Bejaoui M, Calvo M, Folch-Puy E, Pantazi E, Pasut G, Rimola A, Ben Abdennebi H, Adam R, Roselló-Catafau J. Polyethylene glycol rinse solution: An effective way to prevent ischemia-reperfusion injury. World J Gastroenterol. 2014 Nov 21;20(43):16203-14.  PubMed PMID: 25473175;

Allard MA, Sebagh M, Baillie G, Lemoine A, Dartigues P, Faitot F, Faron M, Boige V, Vitadello F, Vibert E, Elias D, Adam R, Goéré D, Sa Cunha A. Comparison  of Complete Pathologic Response and Hepatic Injuries Between Hepatic Arterial Infusion and Systemic Administration of Oxaliplatin in Patients with Colorectal Liver Metastases. Ann Surg Oncol. 2014 Dec 2. In Press.  PubMed PMID:  25448804.

Allard MA, Saffroy R, de la Maisonneuve PB, Ricca L, Bosselut N, Hamelin J, Lecorche E, Bejarano MA, Innominato P, Sebagh M, Adam R, Morère JF, Lemoine A. Colorectal liver metastases are more often super wild type. Toward treatment based on metastatic site genotyping? Target Oncol. 2014 Nov 26. In Press.  PubMed PMID: 25420993.

Faitot F, Faron M, Adam R, Elias D, Cimino M, Cherqui D, Vibert E, Castaing D, Cunha AS, Goéré D. Two-stage hepatectomy versus 1-stage resection combined with radiofrequency for bilobar colorectal metastases: a case-matched analysis of surgical and oncological outcomes. Ann Surg. 2014 Nov;260(5):822-8.  PubMed PMID: 25379853.

Parkin E, O'Reilly DA, Adam R, Kaiser GM, Laurent C, Elias D, Capussotti L, Renehan AG; LiverMetSurvey Centres. Equivalent survival in patients with and without steatosis undergoing resection for colorectal liver metastases following  pre-operative chemotherapy. Eur J Surg Oncol. 2014 Nov;40(11):1436-44.  PubMed PMID: 25189474.

Sebagh M, Allard MA, Cunha AS, Ruiz A, Araujo R, Lemoine A, Paule B, Delvart V, Cherqui D, Vibert E, Adam R. A proposed new method for assessing the pathological response to chemotherapy in resected colorectal liver metastases. Br J Cancer. 2014 Jul 29;111(3):470-6.  PubMed PMID: 25072303;

Adam R, Bilbao-Ramos P, López-Molina S, Abarca B, Ballesteros R, González-Rosende ME, Dea-Ayuela MA, Alzuet-Piña G. Triazolopyridyl ketones as a novel class of antileishmanial agents. DNA binding and BSA interaction. Bioorg Med Chem. 2014 Aug 1;22(15):4018-27.  PubMed PMID: 24953952.

Vibert E, Pittau G, Gelli M, Cunha AS, Jamot L, Faivre J, Castro Benitez C, Castaing D, Adam R. Actual incidence and long-term consequences of posthepatectomy liver failure after hepatectomy for colorectal liver metastases.  Surgery. 2014 Jan;155(1):94-105.  PubMed PMID: 24694360.

Rong Z, Martel G, Vandenbroucke-Menu F, Adam R, Lapointe R. Impact of peri-operative bevacizumab on survival in patients with resected colorectal liver metastases: an analysis of the LiverMetSurvey. HPB (Oxford). 2014 Apr;16(4):342-9.  PubMed PMID: 24641317;

Adam R, Bhangui P. Reply to Letter: "Resection or Transplantation for Early Hepatocellular Carcinoma in a Cirrhotic Liver: Does Size Define the Best Oncological Strategy?" Ann Surg. 2014 Mar 13. In Press.  PubMed PMID:  24633019.

Adam R. Surrogate markers of overall survival in metastatic colorectal cancer: an evolving challenge still more complex with repeat surgery. Ann Surg Oncol. 2014 Jun;21(6):1763-4.  PubMed PMID: 24510185.

Schwaibold EM, Bartels I, Küster H, Lorenz M, Burfeind P, Adam R, Zoll B. De  novo duplication of chromosome 16p in a female infant with signs of neonatal hemochromatosis. Mol Cytogenet. 2014 Jan 23;7(1):7.  PubMed PMID: 24456940;

Allard MA, Sa Cunha A, Ruiz A, Vibert E, Sebagh M, Castaing D, Adam R. The postresection alpha-fetoprotein in cirrhotic patients with hepatocellular carcinoma. An independent predictor of outcome. J Gastrointest Surg. 2014 Apr;18(4):701-8.  PubMed PMID: 24402605.

Allard MA, Adam R. Reply letter to: Simultaneous surgical treatment for both  colorectal liver metastases and peritoneal carcinomatosis. Eur J Surg Oncol. 2014 Mar;40(3):368-9.  PubMed PMID:  24370282.

Viganò L, Capussotti L, Lapointe R, Barroso E, Hubert C, Giuliante F, Ijzermans JN, Mirza DF, Elias D, Adam R. Early recurrence after liver resection for colorectal metastases: risk factors, prognosis, and treatment. A LiverMetSurvey-based study of 6,025 patients. Ann Surg Oncol. 2014 Apr;21(4):1276-86.  PubMed PMID: 24346766.

Bhangui P, Salloum C, Lim C, Andreani P, Ariche A, Adam R, Castaing D, Kerba  T, Azoulay D. Portal vein arterialization: a salvage procedure for a totally de-arterialized liver. The Paul Brousse Hospital experience. HPB (Oxford). 2014 Aug;16(8):723-38.  PubMed PMID: 24329988;

 

Mise à jour le : 22/04/2015

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