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Francis Lévi, Warwick Medical School, University of Warwick, July 21, 2014:

- Circadian control of xenobiotic carcinogenesis and cancer pharmacology

- Toward Systems Cancer Chronotherapeutics and its integration into home care 

La Société Francophone de Chronobiologie (SFC) organise son 44ème congrès qui se déroulera du 29-31 octobre 2014

Séance de la Société de Biologie " La chronobiologie " aura lieu le 15 octobre 2014 de 15h00 à 18h00 Institut Curie-Pavillon Curie Amphithéâtre Marie Curie 11, rue Pierre et Marie Curie – Paris 5ème

La soutenance de thèse de Melle Véronique ROCHE sera présentée le 21 mai 2014

Reportage BBC, 13 mai 2014  Chronotherapy: The science of timing drugs to our Body

Journal "Le monde" le 30 avril 2014, "Quand l'horloge biologique se détraque"

 

Voir la suite

Contact

UMRS 935

Equipe3 : Chronothérapie des cancers

et optimisation de la fonction hépatique

INSERM et Université Paris Sud

Bât A 3ème étage Campus CNRS
7 rue Guy Môquet
94801 Villejuif Cedex (France)
Tel :  +33 (0) 1 49 58 34 83
Fax : +33 (0) 1 49 58 34 59
Email:gladys.germe@inserm.fr

Home Production scientifique Publication

2010 

Bouchahda M., Macarulla T., Liedo G., Lévi F., Elez E., Paule B., Karaboué A., Artru P., Tabernero J., Machover D., Innominato P., Goldschmidt E., Bonnet D., Ducreux M., Castagne V., Guimbaud R. : Shéma simplifié (toutes les 2 semaines) pour le cetuximab dans le cancer colorectal avancé : une analyse rétrospective multicentrique. Les Journées Francophones d’Hépato-gastroentérologie et d’Oncologie Digestive. JFHOD 2010, Paris, 25-28 Mars 2010. (Poster)

Bouchahda M., Karaboué A., Saffroy R., Innominato P., Guettier-Bouttier C., Adam R., Gorden L., Lévi F. : Mutations acquises du gène KRAS dans le développement de métastases d’un cancer colorectal : implications possibles dans le traitement et le pronostic. Les Journées Francophones d’Hépato-gastroentérologie et d’Oncologie Digestive. JFHOD 2010, Paris, 25-28 Mars 2010. (Poster)

Lévi F. : Irinotecan et chronothérapie. Atelier petit-déjeuner : Chimiothérapie intra-artérielle hépatique : « le retour » . Une arme de plus pour le traitement des métastases hépatiques des cancers colorectaux. Les Journées Francophones d’Hépato-gastroentérologie et d’Oncologie Digestive. JFHOD 2010, Paris, 25-28 Mars 2010. (Présentation orale)

Lévi F. on behalf of the  TEMPO Consortium :  Designing personnalized cancer chronotherapeutics. Society for Research on Biological Rhythms 12th Biennial Meeting, May 22-26th 2010, Sandestin, USA (Présentation orale)

Ahowesso C., Li X.M., Scaglione F., Guettier C., Okyar A., Zampera S., Dulong S., Bareggi S., Hossard V., Pirovano M., Delaunay F., Lévi F. : Gender and genetic differences in circadian clocks and pharmacology determine distinct chronotoxicity classes for irinotecan. Society for Research on Biological Rhythms 12th Biennial Meeting, May 22-26th 2010, Sandestin, USA (Poster)

Filipski E., Beau J., Lévi F. : Effect of a cell cycle inhibitor seliciclib on circadian timing system. Society for Research on Biological Rhythms 12th Biennial Meeting, May 22-26th 2010, Sandestin, USA (Poster)

Dulong S, Ballesta A, Hennig L, Abbara C, Clairambault J, Lévi F : In vitro molecular chronopharmacology of anticancer drug irinotecan on human cancer cells. Society for Research on Biological Rhythms 12th Biennial Meeting, May 22-26th 2010, Sandestin, USA(Poster)

Li X.M., Delaunay F., Dulong S., Claustrat B., Teboul M., Beau J., Wu M.W., Lévi F. : Control of cancer progression through reinforcement of host circadian physiology and rhythmic induction of tumor stress genes with circadian meal timing. Society for Research on Biological Rhythms 12th Biennial Meeting, May 22-26th 2010, Sandestin, USA(Poster)

Levi F., Bouchahda M., Ducreux M., Karaboué A., Focan C. N. J., Rougier P., Innominato P., Smith D., Awad S., Adam R. : Optimal control of liver metastases with intravenous cetuximab and hepatic artery infusion of three-drug chemotherapy in patients with liver-only metastases from colorectal cancer. a European multicenter phase II trial. Proc. American Society of Clinical Oncology, 46 th Annual Meeting, June 4th-June 8th 2010, Chicago, USA, J. Clin. Oncol., : abst. # TPS 198. (Poster)

Iurisci I., Valet F., Giacchetti S., Delaloge S., Brain E., Pierga J. Y., de Thé H., Sigal-Zafrani B., Marty M. E., Levi F.: Relations of circadian clocks genes with endocrine, proliferation, differentiation and P53 mutation status in human locally invasive primary breast cancer. Proc. American Society of Clinical Oncology, 46 th Annual Meeting, June 4th-June 8th 2010, Chicago, USA, J. Clin. Oncol., abst. # 10589 (Poster)

Lévi F. : Toward Tailoring Cancer Treatments Through Mathematical Modeling of Circadian Dynamics. RIMM-2010 First International Workshop on The Role and Impact of Mathematics in Medicine. Paris, France, June 10-12, 2010.

Lévi F. : Systems biology approach to the personalization of cancer chronotherapeutics. Workshop “From systems biology to systems medicine”. Workshop organisé par la Commission Européenne, Bruxelles, Belgique, 14-15 Juin 2010. (Expert invité)

Lévi F. : Chronotolerance versus chronoefficacy of anticancer drugs. The UK Clock Club, Stevenage, UK, June 17th 2010. (Invité)

Lévi F. : From circadian control of PK/PD to personalized cancer chemotherapy and chronotherapeutics. 16th World Congress of Basic and Clinical Pharmacology (WorldPharma 2010), Copenhagen, Denmark, 17 - 23 July 2010. (Invité)

Lévi F. : The circadian timing system: implications for the personalization of anticancer drug delivery. Workshop session on “Circadian clocks for drug development and therapeutics” 16th World Congress of Basic and Clinical Pharmacology (WorldPharma 2010), Copenhagen, Denmark, 17 - 23 July 2010. (Organisateur)

Goldbeter A., Altinok A., Lévi F. : Identifying mechanisms of chronotolerance and chronoefficacy for anticancer drugs. Workshop session on “Circadian clocks for drug development and therapeutics” 16th World Congress of Basic and Clinical Pharmacology (WorldPharma 2010), Copenhagen, Denmark, 17 - 23 July 2010. (Invité)

Clairambault J. : Cell proliferation, circadian rhythm, tumour growth and cancer chronotherapeutics. Workshop session on “Circadian clocks for drug development and therapeutics” 16th World Congress of Basic and Clinical Pharmacology (WorldPharma 2010), Copenhagen, Denmark, 17 - 23 July 2010. (Invité)

Scully C.G., Liu W., Meyer J., Dementyev A., Chon K.H., Innominato P., Lévi F., Gorbach A.M. : Time-Frequency Analysis of Skin Temperature in a Patient with a Surface Tumor Monitored with Infrared Imaging. In : Proc. 10th International Conference on Quantitative InfraRed Thermography, July 27-30, 2010, Québec (Canada), X.P.V. Maldague Ed., E. du CAO, Les Eboulements (Quebec), Canada, 993 p.

Giacchetti S. : Gender, a critical determinant of chronotherapeutic efficacy in the metaanalysis of Phase III trials of chronotherapy in 842 patients with metastatic colorectal cancer. International Strategy Meeting on Clinical and Translational Research for Cancer Chronotherapy, 42ème Congrès Annuel de la Société Francophone de Chronobiologie, 8-11 Septembre 2010, La Colle sur Loup, France.

Innominato P. : Dynamics of circadian-related symptoms and rest-activity rhythms in patients on chemotherapy: relevance for the success of cancer chronotherapeutics. International Strategy Meeting on Clinical and Translational Research for Cancer Chronotherapy, 42ème Congrès Annuel de la Société Francophone de Chronobiologie, 8-11 Septembre 2010, La Colle sur Loup, France.

Clairambault J. : Model-based optimization  of chronotherapeutic delivery. International Strategy Meeting on Clinical and Translational Research for Cancer Chronotherapy, 42ème Congrès Annuel de la Société Francophone de Chronobiologie, 8-11 Septembre 2010, La Colle sur Loup, France.

Bouchahda M. : Targeting chronotherapeutic delivery in the liver for enhancing resection rates of colorectal cancer liver metastases: a European  Phase II trial (OPTILIV). International Strategy Meeting on Clinical and Translational Research for Cancer Chronotherapy, 42ème Congrès Annuel de la Société Francophone de Chronobiologie, 8-11 Septembre 2010, La Colle sur Loup, France.

Lévi F. : Cancer chronotherapeutics: concepts and designs revisited. International Strategy Meeting on Clinical and Translational Research for Cancer Chronotherapy, 42ème Congrès Annuel de la Société Francophone de Chronobiologie, 8-11 Septembre 2010, La Colle sur Loup, France. (Organisateur)

Lévi F., Parganiha A., Dugué P.A., Karaboué A., Innominato P., and Waterhouse J. for the Chronotherapy Group of ARTBC International : Pooled analysis of rest‐activity rhythm as a prognostic factor for progression‐free survival and overall survival in patients with metastatic colorectal cancer. International Strategy Meeting on Clinical and Translational Research for Cancer Chronotherapy, 42ème Congrès Annuel de la Société Francophone de Chronobiologie, 8-11 Septembre 2010, La Colle sur Loup, France.

Beau J., Lévi F. : Continuous monitoring of surface or core body temperature in cancer patients : why and how? International Strategy Meeting on Clinical and Translational Research for Cancer Chronotherapy, 42ème Congrès Annuel de la Société Francophone de Chronobiologie, 8-11 Septembre 2010, La Colle sur Loup, France.

Lévi F. : Toward the personalization of cancer chronotherapeutics. The 11th International Conference on Systems Biology, Edinburgh - October 10th-16th 2010. (Invité)

Lévi F. : Personalized chronotherapeutics for improving cancer care, 21st annual European Students’ Conference, 14th  – 17th October 2010. (Invité)

Rajnai Z., Méhn D., Beéry E., Abonyi T., Okyar A., Jani M., Tóth G.K., Fulop F., Lévi F., Krajcsi P. : Seliciclib(R-Roscovitine) is a selective ABCB1 substrate. 9th International ISSX Meeting (International Society for the Study of Xenobiotics), September 4 - 8, 2010, Istanbul, Turkey. (Poster)

Iurisci I., Valet F., Giacchetti S., Pierga J.Y., André F., De Cremoux P., Asselain B., Delaloge S., de Thé H., Spyratos F., Brain E., Sigal-Zifrani B., Mignot L., Marty M., Lévi F. : Circadian Clock Genes in Primary Breast Cancer: Strong Predictors of Pathologic Response on Neoadjuvant Chemotherapy. 33rd Annual San Antonio Breast Cancer Symposium, December 8 - 12, 2010, San Antonio, Texas, USA. (Poster)

Lévi F. : Impact des thérapies ciblées sur le traitement du cancer colorectal métastatique. Journées de Chirurgie du Centre Hépato-Biliaire, Paris, 19-20 Juin 2009 (Invité)

Lévi F. : L’horloge circadienne, cible thérapeutique en cancérologie. Journée de Cancérologie de l’Hôpital Paul Brousse, Villejuif, 4 Décembre 2009 (Co-organisateur)

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Mise à jour le : 22/04/2015

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